San Francisco's Asian Art Museum has occupied the former main library since 2003. It's vast collection has been built upon donations from Avery Brundage and Chong-Moon Lee among others. Even a cursory viewing of the 18,000 objects in the collection will convince you that, as the website says, "Asia is not one place."
Currently on display outside the front door of the museum is a sculpture by Yoshitomo Nara, entitled Your Dog. According to the museum, Nara's "blending of cute, creepy, and vulnerable" has earned him a cult following and comparisons to Jeff Koons and Keith Haring.
Early in the fourth Nicole Tang Noon mystery, Nicole pops into the Asian on her way to the Main Library. Both stand along the eastern edge of San Francisco's Civic Center. You'll have to read the book when it comes out this summer to find out why she goes there (beyond the obvious, to see great art).